The traffic flow is in your favor if you travel west or south to work in the morning. Also depends on how long you want your commute and if public schools are ok. I just bought in La Jolla and my commute to La Mesa is about 25 minutes (no traffic). Good public schools. Also look at:
Tierrasanta
Carmel valley
Scripps ranch
other areas are nice but middle and high schools are a bit sketchy in most San Diego Unified schoold district areas…
