Not all the lots there along soderblom are a full 10k sf lots… several are in the 8k sf range. (Still big). And a lot of the houses are more like 2k sf.
You might consider an east UC neighborhood as well. Look at the homes on Dirac, Pavlov, Bromfield… especially the ones that back to the canyon. Large lots, many with views.
And there are other small pockets – newer homes (compared to your mentioned neighborhood and the one I mentioned which are early 60’s era) –
Lahitte Ct, Hurd/Millikan/Willard.
The homes along the canyon – Wellesley, Mercer Lane, Condon…
Clairemont also has pockets. Some of the homes on Avati and it’s side streets are on larger lots with peek-a-boo views of the bay.
You need to look at individual houses/lots. UC in general has a 5k nominal lot size. So often you’ll get 5k sf lots on one side of the street (non canyon side) and 17k lots on the other side. Same is true in Clairemont.
In general – the older the neighborhood the wider the lots… My hood has an issue keeping postal carriers – every time we get a new postal carrier they apply for a new route because they realize the homes are spread apart and are old-school with the mailboxes at the front door. Too much walking.