Whole-house fans should not be used at night. THey should be used in the evening to cool the house off, then shut down.
If your house is well-sealed from the attic, this will clear the attic as well. Pulls air in from the windows, up through the fan, into the attic, and out the attic vents.
If your attic is not well sealed, though, it can end up blowing attic air back into the house.