I prefer two story cause when the missus gets cranky the second floor is a good place to escape to. Stairs are becoming a problem but I’d make sure to get “facilities” and a bedroom on the first floor. I blew my knee out a few years ago and three months of no bedroom or shower on the first floor got real old. Two stories are nice if there’s a view and an astronomer in the house. Cathedral ceilings are also a nice complement to the grand piano. Personally, I’m hooked on two story. Gets real quiet and when the furnace gets the house warm there’s no beating it.