Few facts my friends in 2007 told me in san diego to justify that the real estate prices in san diego would never go down. Those facts still remain intact:
1) SD is locked between ocean n desert thus limited land here
2) best weather , everyone wants to live here
3) a lot of rich people in san diego
4) awesome companies like qcom n now illumina
These facts are still facts even today.
Few of my friends commute from TV to SV, they strongly advise against it if possible.