It is always possible that there is no physical reality–in the commonly accepted definition. This has always been one premise of metaphysics–that the reality we experience is nothing more than the physical manifestation of
thought–individually or collectively.

From this perspective, I can understand how substituting bits and bytes of information could easily fit into this premise on a scientific level.

Sans physicality, it is also easy to see how life, in that form, could go on forever, and yet, at that point in the equation, it might be necessary to redefine life itself.

Imo, as long as life and death exist, the search for immortality will continue. Personally, I think the scientific and spiritual premises of this quest are quite compatible. More so than one might think.