I guess my questions would be about what your plans on for housing in your new location.
Since it might be temporary (since you might move back here) – does it make more sense to rent. (Transaction costs on short term ownership can kill you.)
If you plan to buy where you’re going – do you have the downpayment/credit bandwidth to finance the new purchase without selling your existing house.
My gut says that if you plan to come back to San Diego, hang on to it.