If you’ve lived in SoCal your whole life and are in a spot where you can pick up and move, then I don’t need to know any more…you should go.
Everyone should enjoy a cross-section of the experiences this country has to offer, and you just can’t do that living in one area your whole life (visiting it just isn’t the same as living it).
Worst case, you move back here in a few years with a great bunch of memories of Colorado. Best case, you love it there and just kicked your life up a few notches.