I would be willing to bet obesity was zero with hunter-gatherers.
Actually, if you take the aggregate of scientific studies, on many of these disorders, the sciences are going away from the “its in the genes” argument. Navydocs post about Dutch Hunger Winter is an interesting study about pre-natal environmental stress that can actually cause dispositions.
But, looking at the other health trends since the late 50s early 60s, obesity is just one of many that are all interconnected and interrelated. Interestingly, it’s not just the US, but the UK as well, and other western states, though, to lesser extent. Actually, I think depression, is the most debilitating financially.