I only have experience along the 15 in Rancho Bernardo (Vista Del Lago). Saw a wonderful place right up against the freeway. Opened the window in the Master Bedroom and could barely hear myself think. Dear goodness, NO!!
I thought hearing major street traffic along Poway Road and Pomerado was bad.
Higher up = prettier views = less absorption of noise
But really there is a varying amount of concern based on the specific situation. From my experience along the 15 freeway, I would say that it is definitely a deal breaker. However, I have no idea how your potential place compares to where I was in terms of dB. You did state that you are two blocks away, I would think that the noise would be minimal at that point if you are facing the right way.
Personally I would like the option to open my windows, sit in my patio/balcony, BBQ outside without being constantly attacked by urban music.