I may have posted here before that one of my kids let a bedroom and attached bath out of their SF flat using AirB&B for about 2-3 years. They had a pushbutton combo lock on the front door which got changed after every “guest” checked out. They had housekeeping come in every time a guest checked out and put everything back together in there like a hotel room. They didn’t do anything special to the rest of the house and left laptops and other valuables sitting around the living room (though I’m not sure they did while at work) and never got anything stolen. AFAIK, they never got any “crazies” …. only grateful guests who were able to get a room and a bath for at least 30% less than a local hotel room (with cooking facilities if they wished) and sans the TOT. Of course, it helped that they were on a bus line and a 1.5 block walk to another busline and less than a mile from SoMA, which is a big transportation hub in SF (and SF public transportation is very cheap).
I think they netted +/- $70 per night when all was said and done (they gave discounts for a week’s stay).
You have to be willing to tolerate someone coming and going in/out of your house at all hours of the night due to being out partying like the tourist that they are.