East Village, but there are big problems also in Little Italy, at least with the homeless. A buddy of mine lives in the Treo building and there are several large homeless camps within a couple of hundred yards of that building. I don’t know about the other neighborhoods.
I don’t worry about the crime as much as the public health issues like TB. People from the suburbs come down to watch a ballgame and end up taking the germs back with them to Rancho Penasquitos or wherever. Bacteria don’t care about how much money you make.
I stay here because I rent a nice, large place for $1.20/sf. Also I’m single and it’s good to be downtown for entertainment purposes. Being single in the suburbs is a drag.