OT – Alcoholism and Addiction

[ocrenter]

[quote=Rustico][quote=ocrenter][quote=Rustico]OCR, What is the highest occurrence of multi-factorial disease that is not alcoholism?[/quote]

most diseases out there are multi-factorial. it is extremely rare to have a disease coming from a specific cause or specific genetic mutation.[/quote]

Playing devils advocate and fishing for the for the frequency of other “multi-factorial” diseases in families. The occurrence is extremely high for combination of alcoholics, chain smoking, drug addicts, eating disorders etc. in the same family. We see things like cleft pallate occuring but much less frequently. We even see entire sibling groups as serious alcoholics pretty often. I am not sure but, I don’t think even asthma afflicts whole families nearly as often as these substance problems? What is the explanation?[/quote]

mood disorders tend to run in families as well. and families filled with folks with “issues” tend to be more stressful. these folks are also more likely to abuse and find ways to self-medicate. then you have the fact that addictive personalities are likely to run in families too.

but then so does hypertension, heart disease, diabetes, breast cancer, colon cancer… all of these are extremely common problems that can run in families but are still very much multi-factorial.

let’s face it, “poly-genetic and multi-factorial” is more the rule rather than the exception. Just like in this world, “shades of gray” is more the rule rather than “black vs white.”

[NotCranky]

Ocrenter, This can be a rhetorical question for thread purposes too.The poly genetic multi-factorial soup theory claims bring up lots of questions.

Yep I understand about the stress.
I’ll say in another way.Given that these families with tons of problems exist, in one of them with seven siblings in which, 3 are alcoholics, 2 are bulimics, one is an anorexic and one is hooked on seven things. How many have the genetic deviation? Would it be more than a family with the rarer case of spina bifida, if so why did it happen? We know these things run in families. Can the suspected genetic markers run as fast? Why what makes them so great? Would six siblings of the spina bifida and other similar issues have the genes but escaped because it is not post birth environment sensitive?

This question can be posed for any subsequent generation you like. Does it matter if both grandfathers and the father or this sibling group died of cirrhosis, as has been frequently the case?

[NotCranky]

Ocrenter, This can be a rhetorical question for thread purposes too.The poly genetic multi-factorial soup theory claims bring up lots of questions.

Yep I understand about the stress.
I’ll say in another way.Given that these families with tons of problems exist, in one of them with seven siblings in which, 3 are alcoholics, 2 are bulimics, one is an anorexic and one is hooked on seven things. How many have the genetic deviation? Would it be more than a family with the rarer case of spina bifida, if so why did it happen? We know these things run in families. Can the suspected genetic markers run as fast? Why what makes them so great? Would six siblings of the spina bifida and other similar issues have the genes but escaped because it is not post birth environment sensitive?

This question can be posed for any subsequent generation you like. Does it matter if both grandfathers and the father or this sibling group died of cirrhosis, as has been frequently the case?

[NotCranky]

Ocrenter, This can be a rhetorical question for thread purposes too.The poly genetic multi-factorial soup theory claims bring up lots of questions.

Yep I understand about the stress.
I’ll say in another way.Given that these families with tons of problems exist, in one of them with seven siblings in which, 3 are alcoholics, 2 are bulimics, one is an anorexic and one is hooked on seven things. How many have the genetic deviation? Would it be more than a family with the rarer case of spina bifida, if so why did it happen? We know these things run in families. Can the suspected genetic markers run as fast? Why what makes them so great? Would six siblings of the spina bifida and other similar issues have the genes but escaped because it is not post birth environment sensitive?

This question can be posed for any subsequent generation you like. Does it matter if both grandfathers and the father or this sibling group died of cirrhosis, as has been frequently the case?

[NotCranky]

Ocrenter, This can be a rhetorical question for thread purposes too.The poly genetic multi-factorial soup theory claims bring up lots of questions.

Yep I understand about the stress.
I’ll say in another way.Given that these families with tons of problems exist, in one of them with seven siblings in which, 3 are alcoholics, 2 are bulimics, one is an anorexic and one is hooked on seven things. How many have the genetic deviation? Would it be more than a family with the rarer case of spina bifida, if so why did it happen? We know these things run in families. Can the suspected genetic markers run as fast? Why what makes them so great? Would six siblings of the spina bifida and other similar issues have the genes but escaped because it is not post birth environment sensitive?

This question can be posed for any subsequent generation you like. Does it matter if both grandfathers and the father or this sibling group died of cirrhosis, as has been frequently the case?

[NotCranky]

Ocrenter, This can be a rhetorical question for thread purposes too.The poly genetic multi-factorial soup theory claims bring up lots of questions.

Yep I understand about the stress.
I’ll say in another way.Given that these families with tons of problems exist, in one of them with seven siblings in which, 3 are alcoholics, 2 are bulimics, one is an anorexic and one is hooked on seven things. How many have the genetic deviation? Would it be more than a family with the rarer case of spina bifida, if so why did it happen? We know these things run in families. Can the suspected genetic markers run as fast? Why what makes them so great? Would six siblings of the spina bifida and other similar issues have the genes but escaped because it is not post birth environment sensitive?

This question can be posed for any subsequent generation you like. Does it matter if both grandfathers and the father or this sibling group died of cirrhosis, as has been frequently the case?

[ocrenter]

[quote=Rustico]Ocrenter, This can be a rhetorical question for thread purposes too.The poly genetic multi-factorial soup theory claims bring up lots of questions.

Yep I understand about the stress.
I’ll say in another way.Given that these families with tons of problems exist, in one of them with seven siblings in which, 3 are alcoholics, 2 are bulimics, one is an anorexic and one is hooked on seven things. How many have the genetic deviation? Would it be more than a family with the rarer case of spina bifida, if so why did it happen? We know these things run in families. Can the suspected genetic markers run as fast? Why what makes them so great? Would six siblings of the spina bifida and other similar issues have the genes but escaped because it is not post birth environment sensitive?

This question can be posed for any subsequent generation you like. Does it matter if both grandfathers and the father or this sibling group died of cirrhosis, as has been frequently the case?[/quote]

poly-genetic multi-factorial doesn’t mean 100% of alcoholics are all poly-genetic multi-factorial. more likely for 100 alcoholics, 33% may be strictly genetic, 33% may be strictly mood disorder related, 33% may be because of the type of weird family structure with increased stressers mixed with addictive personality trait.

[ocrenter]

[quote=Rustico]Ocrenter, This can be a rhetorical question for thread purposes too.The poly genetic multi-factorial soup theory claims bring up lots of questions.

Yep I understand about the stress.
I’ll say in another way.Given that these families with tons of problems exist, in one of them with seven siblings in which, 3 are alcoholics, 2 are bulimics, one is an anorexic and one is hooked on seven things. How many have the genetic deviation? Would it be more than a family with the rarer case of spina bifida, if so why did it happen? We know these things run in families. Can the suspected genetic markers run as fast? Why what makes them so great? Would six siblings of the spina bifida and other similar issues have the genes but escaped because it is not post birth environment sensitive?

This question can be posed for any subsequent generation you like. Does it matter if both grandfathers and the father or this sibling group died of cirrhosis, as has been frequently the case?[/quote]

poly-genetic multi-factorial doesn’t mean 100% of alcoholics are all poly-genetic multi-factorial. more likely for 100 alcoholics, 33% may be strictly genetic, 33% may be strictly mood disorder related, 33% may be because of the type of weird family structure with increased stressers mixed with addictive personality trait.

[ocrenter]

[quote=Rustico]Ocrenter, This can be a rhetorical question for thread purposes too.The poly genetic multi-factorial soup theory claims bring up lots of questions.

Yep I understand about the stress.
I’ll say in another way.Given that these families with tons of problems exist, in one of them with seven siblings in which, 3 are alcoholics, 2 are bulimics, one is an anorexic and one is hooked on seven things. How many have the genetic deviation? Would it be more than a family with the rarer case of spina bifida, if so why did it happen? We know these things run in families. Can the suspected genetic markers run as fast? Why what makes them so great? Would six siblings of the spina bifida and other similar issues have the genes but escaped because it is not post birth environment sensitive?

This question can be posed for any subsequent generation you like. Does it matter if both grandfathers and the father or this sibling group died of cirrhosis, as has been frequently the case?[/quote]

poly-genetic multi-factorial doesn’t mean 100% of alcoholics are all poly-genetic multi-factorial. more likely for 100 alcoholics, 33% may be strictly genetic, 33% may be strictly mood disorder related, 33% may be because of the type of weird family structure with increased stressers mixed with addictive personality trait.

[ocrenter]

[quote=Rustico]Ocrenter, This can be a rhetorical question for thread purposes too.The poly genetic multi-factorial soup theory claims bring up lots of questions.

Yep I understand about the stress.
I’ll say in another way.Given that these families with tons of problems exist, in one of them with seven siblings in which, 3 are alcoholics, 2 are bulimics, one is an anorexic and one is hooked on seven things. How many have the genetic deviation? Would it be more than a family with the rarer case of spina bifida, if so why did it happen? We know these things run in families. Can the suspected genetic markers run as fast? Why what makes them so great? Would six siblings of the spina bifida and other similar issues have the genes but escaped because it is not post birth environment sensitive?

This question can be posed for any subsequent generation you like. Does it matter if both grandfathers and the father or this sibling group died of cirrhosis, as has been frequently the case?[/quote]

poly-genetic multi-factorial doesn’t mean 100% of alcoholics are all poly-genetic multi-factorial. more likely for 100 alcoholics, 33% may be strictly genetic, 33% may be strictly mood disorder related, 33% may be because of the type of weird family structure with increased stressers mixed with addictive personality trait.

[ocrenter]

[quote=Rustico]Ocrenter, This can be a rhetorical question for thread purposes too.The poly genetic multi-factorial soup theory claims bring up lots of questions.

Yep I understand about the stress.
I’ll say in another way.Given that these families with tons of problems exist, in one of them with seven siblings in which, 3 are alcoholics, 2 are bulimics, one is an anorexic and one is hooked on seven things. How many have the genetic deviation? Would it be more than a family with the rarer case of spina bifida, if so why did it happen? We know these things run in families. Can the suspected genetic markers run as fast? Why what makes them so great? Would six siblings of the spina bifida and other similar issues have the genes but escaped because it is not post birth environment sensitive?

This question can be posed for any subsequent generation you like. Does it matter if both grandfathers and the father or this sibling group died of cirrhosis, as has been frequently the case?[/quote]

poly-genetic multi-factorial doesn’t mean 100% of alcoholics are all poly-genetic multi-factorial. more likely for 100 alcoholics, 33% may be strictly genetic, 33% may be strictly mood disorder related, 33% may be because of the type of weird family structure with increased stressers mixed with addictive personality trait.

[NotCranky]

Thanks for sticking with me.That 33% for genetic component alcoholism seems very high to me compared to other poly-genetic multi-factorial disease occurrences in families.

[NotCranky]

Thanks for sticking with me.That 33% for genetic component alcoholism seems very high to me compared to other poly-genetic multi-factorial disease occurrences in families.

[NotCranky]

Thanks for sticking with me.That 33% for genetic component alcoholism seems very high to me compared to other poly-genetic multi-factorial disease occurrences in families.

[NotCranky]

Thanks for sticking with me.That 33% for genetic component alcoholism seems very high to me compared to other poly-genetic multi-factorial disease occurrences in families.

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