Laura, I can answer it for Ren, it was a sarcastic joke. There are no vampires or demons in Murrieta, it is one of the more conservative and religious enclaves in the region, the fact is there are many threads comparing and contrasting the two towns and they are essentially the same town, which occupy the same valley with very few differences and no geographical barrier.
If you seek vampires, I say go north, the twilight series and the lost boys were all set in the pacific northwest, if there are vampires in North America, that is where you will find them (sorry, another sarcastic remark).