If you can do your work from anywhere and don’t need to commute, there’s few reasons to live in an expensive city like San Diego. I work in biotech, so I have to physically be close to my job and every extra mile of commute costs in both time and dollars.
Vegas does get very hot in the summers and colder than SD in the winter. If you’d be flying out here every other weekend some of your cost savings might get eaten up pretty quickly on plane flights.