I would wait until your wife can enter the job market and contribute. If you don’t have the down payment then you probably don’t have sufficient emergency funds either. I know it sucks to pay more in rent than a mortgage costs, but if you can’t save as a renter then be very careful buying. The only exception I would make is if you can get a family member to loan you the down or if you have a nice nest egg in your 401K then I think now is an excellent time to buy.