Tax wise you might want to see if your company offers a dependant care account which can reduce your taxable income. I believe the limit is 5K. If you and your wife are both working find see if one of you is over the SSI (around 97K) limit as it is that person who will see less value from the reduction.
The other area to look at is the Flex spending accounts. I have found these 2 things helpful with respect to lowering my taxes.
Last but not least consider getting your real estate licenses, insurance licenses, or any other license that allows you the ability to set up the shell for a small business. Or find a small business that you could run as a passive manager. This then provides you with a host of other tax deducitons.