I think you could definitely afford a nice house in Woodland Hills for that money, but like everywhere, prices have gone up a bit with this lack of inventory and low interest rates. Still, if you’re really interested, definitely check it out.
Compared to Valencia, the houses in WH are older/have more character, and the lots tend to be bigger. There are more tree-lined streets in WH, etc. which give it a totally different vibe compared to the newness and “sameness” of Valencia. I should note that the people I know who’ve moved to Valencia have no problem with this. If safety and schools are your top priorities, Valencia would probably be a better bet.
At this moment, rents everywhere are pretty high and appear to keep climbing. 🙁