TG, what you indicate only applies to the low to low-mid price ranges in SD. The mid-high to high price ranges have gotten slammed just like everywhere else. If you have 750k to spend you are going to get a house that sold for 1M-1.2M at the peak. That is a pretty healthy discount IMHO. I am talking premium locations like mission hills, point loma, etc.
As far as NP, if I had 500-600k to spend I think I would look hard at mission hills. Right now, the mission hills premium as compared to NP seems low. For example here a few that recently closed in north mission hills.