I think the thing that makes a lot of sense to me is that your liver processes the alcohol. So if alcoholics lack this particular enzyme that allows it to process alcohol like non-alcoholics, that seems compelling to me. Again, that’s not to say they have carte blanche to go on drinking sprees for the rest of their lives. Just means they will have a more difficult time not drinking than others. Not impossible. Just more effort. It will take more will-power than someone who does not have this issue, I suppose.