Big Box stores sure, a few restaurants in the right locations, a few auto-parts stores, supper markets etc..
Touristy type shops in touristy places.
I am seeing more and more empty strip malls even within big city locations (in LA even).
Our favorite restaurant (that would be open until midnight) in a strip mall near LAX was closed down when we went there last month. Made me sad a little as it was convenient to grab something nice to eat coming home late from LAX. The whole mall was about 2/3 empty and it was next to a ranch-99.