I’d also guesstimate in the 250-300K range. But you may have issues qualifying for the best rates on income from new jobs. Significant assets (e.g. 500K retirement funds) certainly helps.
Anyway, with 200K down if it were me and I wanted to be close to the best San Diego has to offer, for 450 – 500K by next year you can probably also get into SFRs in Bay Park or Bay HO/ West Clairemont, have Ocean Breezes (no A/C) and be 10 minutes or so from from downtown, Old Town, Mission Beach, Point Loma, La Jolla, Jack Murphy Stadium, Petco Park, etc…